In San Jacinto County a woman's house is in a state of decay and threatening to collapse after becoming overrun with more than sixty cats

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Many of them are sick and the Houston SPCA is called in to carry out a rescue on a huge scale. Once on the scene the team discovers a litter of newborns hidden under a bed. They're in poor shape and it's a race against time to get them back to the shelter. In Houston, Investigator Shawna Sundberg has to take immediate action when she stumbles upon a family of dogs in desperate need of medical care while in Liberty County Investigator Debbie Michielson gets more than she bargained for when she arrives at a trailer park to discover newborn puppies hidden in a disused shed.